New detection techniques for axion dark matter

The axion is one of the best motivated dark matter candidates, simultaneously solving the Strong CP problem as well as providing the dark matter of the universe. However, in comparison to WIMPs the axion was historically neglected by experimental efforts. This has been changing in the last five years, which a bevy of new experiment proposals and results. I outline several recent updates for new detection ideas, including plasma haloscopes and axion detection with phonon-polaritons.

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Through Fulbright Scholar Program, UK geology professor unravels the erosion of the Appalachians — from Ireland

A portrait of a professor.
Dave Moecher

By Kent Ratajeski

Dave Moecher, a professor in the University of Kentucky Department of Earth and Environmental Sciences, recently returned from Ireland, where he spent five months studying the erosion of the Appalachian Mountains and exploring the culture and history of the Emerald Isle.

Understanding and manipulating metallohomeostasis of an opportunistic fungal pathogen

Denning-Jannace

Transition metals such as Fe, Cu, and Zn are micronutrients that have critical roles at the host-pathogen interface as both the host and pathogen need them for survival. The host has developed innate immune strategies to sequester metals such as Fe which pathogens need for survival as well as strategies to secrete certain metals such as Cu to exert toxic effects on the pathogen. In return, pathogens have evolved strategies to scavenge metals they need, as well as export or store excess metal. Candida albicans, is an opportunistic fungal pathogen that has the capacity to cause systemic infections that can lead to death in immunocompromised and immunosuppressed populations. Azoles, such as fluconazole, are one of the four classes of antifungals that are FDA approved and are a first line treatment for C. albicans infections.  Our lab has shown significant changes to metallohomeostasis of C. albicans as a result of fluconazole treatment. In this talk, I will discuss our work to determine how C. albicans overcomes azole treatment by modifying Cu homeostasis pathways. I will also discuss a potential strategy that focuses on metal dyshomeostasis and takes advantage of our innate immune system to develop a possible treatment for C. albicans infections.

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CP 114

UK professor recognized by ESPN2 for ‘Going the Extra Yard’

By Lindsey Piercy

LEXINGTON, Ky. (Oct. 26, 2022) — Keaton Upshaw, a senior tight end for the Kentucky Wildcats, understands the demand of one of football’s true hybrid positions.

Running routes and catching passes on one play, then blocking a linebacker the next, means taking extra steps in practice to be prepared. It means sometimes going the extra yard.

On the gridiron, Upshaw has coaches to guide him. But off the field, he also has someone who is encouraging him to do more, learn more and be more.

UK’s Pi Sigma Alpha Chapter Wins National 2022 Best Chapter Award

By Nizhoni McDarment

LEXINGTON, Ky.  -- The University of Kentucky’s Delta Chapter of Pi Sigma Alpha, the National Political Science Honors Society, recently received a Best Chapter Award for the 2021-22 school year.

The UK chapter was one of six institutions, similar in size, to receive this award out of more than 800 Pi Sigma Alpha Chapters in the United States.

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