Department of Biology Outreaching to the Community
June 15, 2023
Within the last two weeks, elementary and middle schools involved with the UK STEM Camp run out of the College of Education sent approximately 200 students to engage in activities with the Department of Biology. The STEM Camp (https://education.uky.edu/stem/camp/) has been running since 2010, and Biology professor Dr. Robin Cooper and his students have been involved with it for a number of years.
Sumanth Manohar, Biology Postdoctoral Research Scholar, Receives the 2023-2024 Knights Templar Eye Foundation’s Career Starter Research Grant
The Knights Templar Eye Foundation is dedicated to funding research into the prevention and treatment of sight threatening diseases in children. Each year, the foundation invites proposals for funding of research related to pediatric ocular disorders. Dr. Sumanth Manohar, a postdoctoral research scholar working in the lab of Dr. Ann Morris in UK’s Department of Biology, was one of 25 scientists selected to receive this funding in 2023-2024.
Click here for more information about Dr. Sarah Tishkoff.
Africa is thought to be the ancestral homeland of all modern human populations. It is also a region of tremendous cultural, linguistic, climatic, and genetic diversity. Despite the important role that African populations have played in human history, they remain one of the most underrepresented groups in human genomics studies. A comprehensive knowledge of patterns of variation in African genomes is critical for a deeper understanding of human genomic diversity, the identification of functionally important genetic variation, the genetic basis of adaptation to diverse environments and diets, and for reconstructing modern human origins. African populations practice diverse subsistence patterns (hunter-gatherers, pastoralists, agriculturalists, and agro-pastoralists) and live in diverse environments with differing pathogen exposure (tropical forest, savannah, coastal, desert, low altitude, and high altitude) and, therefore, are likely to have experienced local adaptation. In this talk I will discuss results of analyses of genome-scale genetic variation in geographically, linguistically, and ethnically diverse African populations in order to reconstruct human evolutionary history in Africa, African and African American ancestry, as well as the genetic basis of adaption to diverse environments.
601 Seminar | "Long-distance Relationships in the Control of Gene Regulation During Development, Disease, and Evolution"
PhD from Université Paris 6 (France)
Group Leader at the European Molecular Biology Laboratory (2006-2015) (Heidelberg, Germany)
Head of Research Unit at the Institut Pasteur (2015-2019) (Paris, France)
Professor, The University of Chicago (2019-.)
The mechanisms that regulate the efficiency and specificity of interactions between distant genes and cis-regulatory elements such as enhancers play a central role in shaping the specific regulatory programs that control cell fate and identity. In particular, the (epi)genetic elements that organize the 3D folding of the genome in specific loops and domains have emerged as key determinants of this process. I will discuss our current views on how 3D genome architecture is organized, how it influences gene regulatory interactions and illustrate how alterations of the mechanisms and elements that organize genomes in 3D could contribute to genomic disorders and genome evolution.
Dr. Chesler received his degrees from Bard College (B.A., 1995) and Columbia University (Ph.D., 2005). His graduate study, in the laboratory of Dr. Stuart Firestein, was focused on the function and development of olfactory sensory neurons. He did his postdoctoral training in the laboratory of Dr. David Julius at the University of California, San Francisco, where he combined physiological, anatomical, and behavioral approaches to study the pharmacology of somatosensory neurons. He joined the NIH intramural pain program (NCCIH) in 2013 where his laboratory now employs multidisciplinary approaches to study how sensory stimuli (such temperature, touch, and environmental irritants) are detected and encoded by the somatosensory system.
Dr. Hobson received her PhD from New Mexico State University and was awarded two independent postdoctoral fellowships, the first at NIMBioS (the National Institute for Mathematical and Biological Synthesis) and the second at the Santa Fe Institute. She started her lab at the University of Cincinnati in Fall 2019 and is currently an Assistant Professor.
In many social species individuals create their social worlds through interaction decisions and are then subject to and constrained by these social constructs, which can affect an individual’s future actions. Understanding how much individuals “know” about their social worlds is critical in understanding these potential feedbacks. However, it is difficult to determine how much information individuals have about the social structures in which they live. In this talk, I summarize several ways my group is addressing these questions by combining empirical experiments with computational approaches to provide insight into cognition through social decisions. I highlight new work on parakeet aggression and dominance hierarchies to illustrate this approach. I show evidence that parakeet rank is unlikely due to individual characteristics and that group-level social dominance patterns can be plastic and can respond to group membership changes. Finally, I show how parallel or related experiments can allow for comparative analyses across species. These approaches, and a taxonomically broad perspective, provide new opportunities to investigate the effect of social information on individual behavior within conflict, and has the potential to provide rigorous evidence for the evolutionary patterns underlying social cognition.
Dr. Barnes is currently a Professor of Zoophysiology with the Institute of Arctic Biology at the University of Alaska in Fairbanks. He's also the Director of Alaska INBRE, an NIH capacity building program in biomedical research and also the Science co-Director at Toolik Field Station. He participated in summer workshops involving biological rhythms at Hopkins Marine Station. He has a PhD in Zoology from the University of Washington where Jim Kenagy was his advisor. Dr. Barnes received his Post-doc in Psychology and Zoology with Irv Zucker and Paul Licht as advisors. He began as Assistant Professor at the University of Alaska in 1986.
In Alaska, winters begin early, last seemingly forever, are very cold, snowy and dark, as well as extremely beautiful, quiet, and serene. This talk will review the physiological and behavioral strategies available to animals for surviving and coping with arctic winters, including cryobiology in insects, freeze tolerance in frogs, and hibernation in ground squirrels and bears. Using data logging and advanced telemetry, the locations, behavior, sleep, circadian rhythms, cardiovascular patterns, and thermoregulation of animals were recorded as they overwinter under natural conditions.
Cucujus beetle larvae may not freeze at temperatures below -80C, wood frogs freeze almost solid and survive; arctic ground squirrels lose track of time, become torpid while colder than ice but warm to sleep, even as black bears continuously doze, only occasionally snore, and their hearts beat in a syncopated rhythm. Little is known about the genetic and molecular basis of hibernation, but discovering its mechanisms could lead to novel clinical therapies and escape strategies in humans.
Watch the seminar here!