Advanced and extended individual research on selected problem of current significance in biomedical engineering.

Advanced and extended individual research on selected problem of current significance in biomedical engineering.

A comprehensive introduction to major aspects of biomedical instrumentation. Topics include basic concept of medical instrumentation, biopotentials, physiological pressure/flow/respiratory measurement, optical sensing, and clinical applications of all the above. The fundamental mathematics underlying each instrument will be reviewed and an engineering picture of the hardware and software needed to implement each system will be examined.

A multidisciplinary approach combining engineering principles for systems analysis and control, knowledge of biological control mechanisms, and computational properties of biological neural networks in the development of engineering neural networks for control applications. Topics include: equivalent circuit models for biological neurons and networks, non-linear differential equation representations, biological control strategies for rhythmic movements, design and development of controller for robot function, proposal development and presentation.

An interdisciplinary course devoted to detailed study of a topic or current significance in biomedical engineering, such as cellular mechanotransduction, systems biology, and tissue engineering.

This is an elective course for graduate students who are interested in learning nano-scale engineering and its applications in biology and medicine. The course covers a broad range of topics in nanobioengineering and nanomedicine, including synthesis, characterization, and functionalization of most common nanomaterials and nanostructures, the interactions between nanoparticles and the biological systems, current state of art in nanomaterial-based molecular imaging, drug/gene delivery, and gene editing and regulation.

Tissue engineering can be defined as the application of principles of engineering, biology, materials science, and medicine to restore, maintain, or improve tissue function. This field evolved from the field of biomaterials development, and the term "tissue engineering" has become largely interchangeable with "regenerative medicine," which also incorporates the research on self-healing. In this course, fundamental engineering and biological principles underlying the field of tissue engineering will be studied, along with case-studies on fabricating specific functional tissues and organs.

This course presents an engineering-based approach to study of the biomechanical design and quantitative function of the human musculoskeletal system. The lectures consist of four parts that examine the constituent materials & structures of the musculoskeletal system and then develops engineering approaches, solutions, and interpretations to static and dynamic human joint loading and movements. Course principles are applied in an end of semester student project.

Special topics in biomedical engineering, addressed primarily in a lecture/discussion format. Presentation of focussed or specialized topics that are not available in standard courses. Lecture, three hours; laboratory, 0-2 hours per week. May be repeated to a maximum of nine credits.

Half-time to full-time work on thesis. May be repeated to a maximum of six semesters.