X-ray Crystallography and infrared transient spectroscopy with nucleic acid crystals

Friday, May 13, 2016 - 4:00pm to 4:50pm
CP - 114
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Christine Cardin will be presenting a Nietzel Visiting Distinguished Faculty Program Seminar titled, "X-ray Crystallography and infrared transient spectroscopy with nucleic acid crystals."

Abstract: Photoactive ruthenium polypyridyl complexes attract worldwide attention because of their potential applications in cancer chemotherapy and because they provide useful tools for studying the fundamentals of electron transfer in DNA. In this talk, the structures of several ruthenium complexes bound to several oligonucleotides will be described. The recent transient infrared spectroscopy (TRIR) study of the photooxidizing [Ru(TAP)2dppz]2+ complex crystallized with the decamer duplex d(TCGGCGCCGA)2 has provided an insight into the earliest steps in guanine photooxidation and hence, DNA damage.

Fabulous Catalysts and the NMR Lab: Anne-Frances Miller

In room 33 of the Chem-Phys building, you’ll find UK’s laboratory for Nuclear Magnetic Resonance Spectroscopy (NMR). The facility's director is Anne-Frances Miller, an associate professor of both Chemistry and Biochemistry.

In this podcast, professor Miller talks about the wide range of applications of NMR, how researchers can use it, and about her own research on enzyme mechanics.

This podcast was produced by Stephen Gordinier.

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