A course which deals with the application of modern analytical methods, primarily instrumental methods, in the determination of the strength, purity, and quality of drugs and pharmaceuticals. Laboratory exercises include analysis of raw materials and finished dosage forms. Lecture, three hours; laboratory, four hours.
Basics of radioactive decay and detection. Labelling of molecules and cells with radionuclides. Imaging systems and clinical aspects of radiopharmaceuticals. Radioanalytical applications in pharmaceutical sciences, including positron tomography and gamma scintigraphy. Development of new radiopharmaceuticals and absorbed dose calculations. The principles of radiation safety and radiobiology.
The course will describe the fundamental concepts, principles and techniques involved in the characterization, development, evaluation and preparation of sterile products. Lecture, two credits; lecture with laboratory, three credits.
The purpose of this course is to teach students about practical aspects of drug metabolism research. This includes addressing the function and purpose of drug metabolism studies, how those studies are carried out, why and how they are done, how metabolites are characterized, and some discussion of the limits and utility of the various approaches used in drug metabolism research.
This course will provide in-depth coverage of the molecular pharmacology of growth factors, transcription factors, receptors, and ion channels. Emphasis will be placed on both the normal functions of these cell-signaling molecules and perturbations that result in several prevalent human diseases, including cancer, Alzheimer's, diabetes, osteoporosis, and inherited human illnesses. Students will be introduced to experimental approaches to diagnosing and treating these illnesses in the light of our evolving knowledge of molecular pharmacology.
May be repeated indefinitely.
The course will discuss basic concepts in physics prior to the 20th century and the backdrop to the emergence of the Special Theory of Relativity. Elements of Special and General Relativity will be discussed at a non-technical level. These concepts will be used to explain how very massive stars inevitably collapse to form black holes. Their observational signatures will be discussed. The work of Hawking leading to the prediction that black holes emit faint radiation will be explained. Finally, the possibility of existence of wormholes leading to time travel will be explored.
A lecture and problem course dealing with advanced topics in atomic physics, including atomic structure, spectra, and interactions of atoms with charged particles and electromagnetic fields. Topics include Rydberg atoms, ionization processes, electron correlations, laser techniques and general theoretical methods.
A seminar for analysis of women's health issues using a global, public health approach incorporating theory, research, and health policy. Topics such as the epidemiology of the leading causes of morbidity and mortality among women, gender roles and health, reproductive health, women's mental health, and women in the health care system will be examined. Students will select a topic from a wide range of women's health issues for in-depth exploration.
This course will provide in-depth coverage of the molecular pharmacology of growth factors, transcription factors, receptors, and ion channels. Emphasis will be placed on both the normal functions of these cell-signaling molecules and perturbations that result in several prevalent human diseases, including cancer, Alzheimer's, diabetes, osteoporosis, and inherited human illnesses. Students will be introduced to experimental approaches to diagnosing and treating these illnesses in the light of our evolving knowledge of molecular pharmacology.
