A multidisciplinary discussion of how the process of aging affects biological systems. Coverage will be quite broad and includes topics such as subcellular and cellular aging, genetics, immunology, anatomy and physiology, animal model of aging, etc.
An explanation of the processes which contribute to the development of the nervous system. Neurophysiological, cell biological and molecular approaches to cell differentiation, neuronal pathfinding and synapse formation and stabilization will be explored and discussed. Examples will be drawn from both vertebrate and invertebrate preparations.
Quantitative treatment of dynamics of drug absorption, distribution, metabolism and excretion, including development of both mathematical models and model-independent approaches for describing these processes.
The objective of this course is to familiarize graduate students with the principles and mechanisms of drug action in biochemical and physiological systems. Students will discuss the quantitative approaches to assessing drug responses, metabolism and toxicity.
Drug metabolism and disposition. Lectures and discussion of the chemistry and biochemistry of drug biotransformation with emphasis on the mixed-function oxidase system.
Maximum of six credits can be applied to master's degree with thesis. May be repeated to a maximum of 12 hours.
This course introduces the principal actions of substances which are used as drugs for treatment of diseases and suffering in humans. It will cover the general principles of drug action, how drugs alter the function of normal and pathologic tissues and organisms and how they influence the disease process. Drugs used in the treatment of disease processes will be integrated with discussion of those diseases in PAT 823. Lecture, 20 hours per week.
With the advice and approval of his or her faculty adviser, the second-year student may choose approved electives offered by the Department of Pharmacology. The intent is to provide the student an opportunity for exploration and study in an area which supplements and/or complements required course work in the second-year curriculum. PASS-FAIL ONLY.
Quantitative treatment of dynamics of drug absorption, distribution, metabolism and excretion, including development of both mathematical models and model-independent approaches for describing these processes.
An overview of the biochemical pathways leading to compounds called natural products.
