This course will provide in-depth coverage of the molecular pharmacology of growth factors, transcription factors, receptors, and ion channels. Emphasis will be placed on both the normal functions of these cell-signaling molecules and perturbations that result in several prevalent human diseases, including cancer, Alzheimer's, diabetes, osteoporosis, and inherited human illnesses. Students will be introduced to experimental approaches to diagnosing and treating these illnesses in the light of our evolving knowledge of molecular pharmacology.