This course is an introduction to the science of environmental pollution with an emphasis on fate and transport of contaminants and adverse effects on biological systems. Pollutants covered include metals, pesticides, organics, radionuclides, nanomaterials, and nutrients. The course covers physiological and toxicological effects of chemicals on natural biota, including considerations at cellular, organismal, population, community, and ecosystem levels. Topics include: absorption, distribution, bioaccumulation, and biomagnification of pollutants; biochemical and physiological mechanisms involved in stress-induced responses and stress reduction; evolution of toxicant resistance and multi-generational effects; fate and transport of contaminants; dose- response modeling; risk assessment, and environmental regulations.