This course will focus on experimentation in neurophysiology. The generation of receptor potentials in sensory neurons will be measured in addition to action potentials in axons. Pharmacological experimentation of ionotropic and metabotropic receptors subtypes and second messengers signaling will be conducted. The key role of ion channels and transporters in regulation of the membrane potential will be examined. The concept of electrochemical equilibrium will be introduced and the quantitative examination of the equilibrium membrane potential will include discussion of Goldman and Nernst equations and their applications. The mechanisms of action potential generation, as a result of synaptic and receptor stimulation within a neural cell, will be measured. Lecture and laboratory. Prerequisites: BIO 302 or BIO 350 or consent of Instructor.

This course will focus on experimentation in neurophysiology. The generation of receptor potentials in sensory neurons will be measured in addition to action potentials in axons. Pharmacological experimentation of ionotropic and metabotropic receptors subtypes and second messengers signaling will be conducted. The key role of ion channels and transporters in regulation of the membrane potential will be examined. The concept of electrochemical equilibrium will be introduced and the quantitative examination of the equilibrium membrane potential will include discussion of Goldman and Nernst equations and their applications. The mechanisms of action potential generation, as a result of synaptic and receptor stimulation within a neural cell, will be measured. Lecture and laboratory. Prerequisites: BIO 302 or BIO 350 or consent of Instructor.