Pharmacokinetics is the study of drug movement from its site of administration, to its distribution in the body and its elimination (via excretion and metabolism) from the body. Pharmacodynamics is the study of timecourse of drug response and those factors associated with the clinical outcome. This course provides the mathematical foundation for describing physiological processes in the body that allow the prediction of how individual variations, concurrent therapy, disease states, non- linear handling and other factors can and do affect steady state drug and metabolite levels, drug dosing, dosing intervals and dosing rates in patients.