Course content includes immunological, biochemical and genetic concepts and molecular biology related to the clinical process of transplantation. Cellular and molecular mechanisms will be an intense focus of this course. Solid organ and tissues transplantation, the need for donor organs and tissues, compatibility requirements for successful transplantation of each type of organ and tissue, immunosuppressive therapy, and research opportunities that may impact successful transplantation and tissue availability will be examined. Literature review and presentation of papers on assigned topics will be required.