An Aspartyl Cathepsin Targeted PET Agent: Application in an Alzheimer's Disease Mouse Model.
| Author | |
|---|---|
| Abstract | :
Early detection of Alzheimer's disease (AD) pathology is a serious challenge for both diagnosis and clinical trials. The aspartyl protease, Cathepsin D (CatD), is overexpressed in AD and could be a biomarker of disease. We have previously designed a unique contrast agent (CA) for dual-optical and magnetic resonance imaging of the activity of the CatD class of enzymes. |
| Year of Publication | :
0
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| Journal | :
Journal of Alzheimer's disease : JAD
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| Volume | :
61
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| Issue | :
3
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| Number of Pages | :
1241-1252
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| Date Published | :
2018
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| ISSN Number | :
1387-2877
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| URL | :
https://content.iospress.com/openurl?genre=article&id=doi:10.3233/JAD-170115
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| DOI | :
10.3233/JAD-170115
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| Short Title | :
J Alzheimers Dis
|
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