Serum IL-17 levels are higher in critically ill patients with AKI and associated with worse outcomes.
| Author | |
|---|---|
| Abstract | :
Interleukin-17 (IL-17) antagonism in rats reduces the severity and progression of AKI. IL-17-producing circulating T helper-17 (TH17) cells is increased in critically ill patients with AKI indicating that this pathway is also activated in humans. We aim to compare serum IL-17A levels in critically ill patients with versus without AKI and to examine their relationship with mortality and major adverse kidney events (MAKE). |
| Year of Publication | :
2022
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| Journal | :
Critical care (London, England)
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| Volume | :
26
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| Issue | :
1
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| Number of Pages | :
107
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| Date Published | :
2022
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| ISSN Number | :
1364-8535
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| URL | :
https://ccforum.biomedcentral.com/articles/10.1186/s13054-022-03976-4
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| DOI | :
10.1186/s13054-022-03976-4
|
| Short Title | :
Crit Care
|
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