Our multidisciplinary research group combines undergraduates, graduate and postdoctoral fellows with expertise in analytical chemistry, biological chemistry and material sciences.

Common theme to all our endeavors is molecular recognition

Dr. Bachas is the director of the following cross-disciplinary programs:
NSF-REU: Polymeric Membrane Materials and Thin Films
Environmental Cross-Disciplinary Training Program

Research summary of Bachas Lab (PDF)

• Ionophore/Synthetic Receptors for Electrochemical and Optical Sensors
• Bionanotechnology
• Toxicology of Nanomaterials
• Nanoscience in Environmental Remediation
• Micromachined Sensors
• Microfabricated Analytical Systems

• K. Turner, S. Xu, P. Pasini, S. Deo, L. Bachas, and S. Daunert, "Hydroxylated Polychlorinated Biphenyl Detection Based on a Genetically Engineered Bioluminescent Whole-Cell Sensing System", Anal. Chem., 79, 5740-5745 (2007).
• A. S. Watts, A. A. Urbas, E. Moschou, V. G. Gavalas, J. V. Zoval, M. Madou, and L. G. Bachas, "Centrifugal Microfluidics with Integrated Sensing Microdome Optodes for Multi-Ion Detection", Anal. Chem., 79, 8046-8054 (2007).
• Y. C. Li, L. G. Bachas, and D. Bhattacharyya, "Selected Chloro-Organic Detoxifications by Poly-Chelate (Poly(acrylic Acid)) and Citrate-Based Fenton Reaction at Neutral pH Environment", Ind. Eng. Chem. Res., 46, 7984-7992 (2007). 
• N. Chopra, V. G. Gavalas, F. J. Hinds, and L. G. Bachas, "Functional One-Dimensional Nanomaterials: Applications in Nanoscale Biosensors", Anal. Lett., 40, 2067-2096 (2007).
• J. D. Ehrick, S. M. Stokes, S. Bachas-Daunert, E. A. Moschou, S. K. Deo, L. G. Bachas, and S. Daunert, "Chemically Tunable Lensing of Stimuli-Responsive Hydrogel Microdomes", Adv. Mater., 19, 4024-4027 (2007).
• E. A. Moschou, L. G. Bachas, and S. Daunert, "Smart Hydrogel Materials" in "Handbook of Biosensors and Biochips", Robert Marks, David Cullen, Christopher Lowe, Howard E. Weetall, Isao Karube, Eds., John Wiley and Sons: New York, NY, Vol. 1, pp. 259-268 (2007).
• J. T. Hastings, J. Guo, P. D. Keathley, P. B. Kumaresh, Y. Wei, S. Law, and L. G. Bachas, "Optimal Self-Referenced Sensing Using Long- and Short-Range Surface Plasmons", Opt. Express, 15, 17661-17672 (2007).
• R. S. Ehrick, M. Capaccio, D. A. Puleo, and L. G. Bachas, "Ligand-Modified Aminobisphosphonate for Linking Proteins to Hydroxyapatite and Bone Surface", Bioconjugate Chem., 19, 315-321 (2008).
• R. D. Johnson, V. Gavalas, S. Daunert, and L. G. Bachas, "Microfluidic Ion-Sensing Devices", Anal. Chim. Acta, 613, 20-30 (2008).
• E. Oesterling, N. Chopra, V. Gavalas, X. Arzuaga, E. J. Lim, R. Sultana, D. A. Butterfield, L. Bachas, and B. Hennig, "Alumina Nanoparticles Induce Expression of Endothelial Cell Adhesion Molecules", Toxicol. Lett., 178, 160-166 (2008).
• G. Ghosh, L. G. Bachas, and K. W. Anderson, "Biosensor Incorporating Cell Barrier Architectures on Ion-Selective Electrodes for Early Screening of Cancer", Anal. Bioanal. Chem., 391, 2783-2791 (2008).
• K. Venkatachalam, X. Arzuaga, N. Chopra, V. G. Gavalas, J. Xu, D. Bhattacharyya, B. Hennig, and L. G. Bachas, "Reductive Dechlorination of 3,3',4,4'-Tetrachlorobiphenyl (PCB77) Using Palladium or Palladium/Iron Nanoparticles and Assessment of the Reduction in Toxic Potency in Vascular Endothelial Cells", J. Hazard. Mater., 159, 483-491 (2008).
• E. J. Lim, Z. Májková, S. Xu, L. Bachas, X. Arzuaga, E. Smart, M. T. Tseng, M. Toborek, and B. Hennig, "Coplanar Polychlorinated Biphenyl-Induced CYP1A1 Is Regulated through Caveolae Signaling in Vascular Endothelial Cells", Chem.-Biol. Interact., 176, 71-78 (2008).
• J. Xu, L. Bachas, and D. Bhattacharyya, "Synthesis of Nanostructured Bimetallic Particles in Polyligand-Functionalized Membranes for Remediation", in "Nanotechnology Applications for Clean Water", M. Diallo, J. Duncan, N. Savage, A. Street, and R. Sustich, Eds., Elsevier, Chapter 22, pp. 311-335 (2009).
• S. Lewis, A. Lynch, L. Bachas, S. Hampson, L. Ormsbee, and D. Bhattacharyya, "Chelate-Modified Fenton Reaction for the Degradation of Trichloroethylene in Aqueous and Two-Phase Systems", Environ. Eng. Sci., 26, 849-859 (2009).
• N. Chopra, L. G. Bachas, and M. R. Knecht, "Fabrication and Biofunctionalization of Carbon-Encapsulated Au Nanoparticles", Chem. Mater., 21, 1176-1178 (2009).
• Y.-H. Tee, L. Bachas, and D. Bhattacharyya, "Degradation of Trichloroethylene by Iron-Based Bimetallic Nanoparticles", J. Phys. Chem. C, 113, 9454-9464 (2009).
• J. D. Ehrick, M. R. Luckett, S. Khatwani, Y. Wei, S. K. Deo, L. G. Bachas, and S. Daunert, "Glucose Responsive Hydrogel Networks Based on Protein Recognition", Macromol. Biosci., 9, 864-868 (2009).